J Ren Nutr 2005;15(3):318-331. However, it’s important to use supplements only as directed, select products that are free of PAs, and consult a healthcare professional before taking them, especially if you’re taking any other medications or have underlying health conditions. View abstract. View abstract. View abstract. Int J Cardiol. Itchy, red skin (eczema). View abstract. View abstract. Evening primrose oil and borage oil in rheumatologic conditions. Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. Improvement is measured as a decrease in the number and severity of tender and swollen joints. View abstract. Wang YP, Yan J, Fu PP, Chou MW. Information from this source is evidence-based and objective, and without commercial influence. Kinderarztl.Prax. However, these compounds are mostly removed during processing and PA-free borage supplements are widely available (17). Borage has been used alone and in combination with fish oil for the treatment of rheumatoid arthritis, skin disorders, and bone weakening, although clinical evidence to support these uses is limited. Borage supplements may cause mild side effects, including digestive problems. Improving the function of the lungs in critically ill patients. To be on the safe side, you should stop taking borage seed oil at least two weeks before surgery. Vaddadi KS. A skin condition in infants called seborrheic dermatitis. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Prostaglandins Leukot.Essent.Fatty Acids 2003;68(3):213-218. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. View abstract. Available for Android and iOS devices. View abstract. Borrek, S., Hildebrandt, A., and Forster, J. View abstract. View abstract. Toxicol Lett 2005;155:411-20. Borage leaves have been used as a potherb and in European herbal medicine since the Middle Ages. View abstract. Internal use of whole borage leaf is not recommended. View abstract. Tollesson, A. and Frithz, A. Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis. View abstract. Unsaturated pyrrolizidines from borage (Borago officinalis), a common garden herb. 6-16-2006;110(2):212-216. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. Larson KM, Roby MR, Stermitz FR. Contraindications have not yet been identified. Henz BM. Martens-Lobenhoffer, J. and Meyer, F. P. Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). J Nat Prod 1984;47:747-8. But borage seed oil seems to work in a different way than NSAIDs. Some chemicals that form when the liver breaks down borage seed oil can be harmful. Medications that cause the liver to break down borage seed oil might enhance the toxic effects of chemicals contained in borage seed oil. Semin Arthritis Rheum 1995;25:87-96. Morse PF, Horrobin DF, Manku MS, et al. Relationship between plasma essential fatty acid changes and clinical response. A placebo-controlled double-blind study]. View abstract. NSAIDs are anti-inflammatory medications used to decrease pain and swelling. View abstract. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Nutr Cancer 1995;24:33-45. . Select one or more newsletters to continue. Supplies Anti-Inflammatory Properties.

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